Use italics for emphasis, not bold (generally speaking).
Don’t use quotation marks for emphasis; it can suggest insincerity, sarcasm, or irony.
On Web pages, do not underline text for emphasis; this will make it look like a link.
Don’t use a combination of bold, underline, or italics. One will do.
Italicize foreign words, but not Latin terms like quid pro quo, de novo, etc.